Cellulose-based hydrogels are immensely important for tissue engineering. In this review, we attempt to document the source, nature, and application of cellulose-based hydrogels as an extracellular matrix for tissue growth and regeneration. Hydrogels can be prepared either from native cellulose, including both bacterial and plant sources or from cellulose derivatives, such as methyl cellulose, carboxymethylcellulose, and hydroxypropylmethylcellulose or even metal ions such as silver. Cellulose-polymer composite (polymers that include natural sources including chitosan, starch, alginates, collagen, hyaluronic acid, and chitin) are an attractive, inexpensive, and advantageous structural material that is easy to use. Cellulose-based scaffolding materials are widely used in the regeneration of various tissues, such as bone, cartilage, heart, blood vessel, nerve, and liver, among others. In this review, we discuss the most important applications of cellulosic hydrogels in tissue engineering based on their structural compositions.

中文翻译：

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功能性纤维素基水凝胶作为组织工程的细胞外基质。


纤维素基水凝胶对于组织工程非常重要。在这篇综述中，我们试图记录纤维素基水凝胶作为组织生长和再生的细胞外基质的来源、性质和应用。水凝胶可以由天然纤维素（包括细菌和植物来源）或纤维素衍生物（例如甲基纤维素、羧甲基纤维素和羟丙基甲基纤维素）或什至金属离子（例如银）制备。纤维素聚合物复合材料（包含壳聚糖、淀粉、藻酸盐、胶原蛋白、透明质酸和甲壳素等天然来源的聚合物）是一种有吸引力、廉价且有利且易于使用的结构材料。纤维素基支架材料广泛应用于骨、软骨、心脏、血管、神经、肝脏等多种组织的再生。在这篇综述中，我们根据纤维素水凝胶的结构组成讨论了纤维素水凝胶在组织工程中最重要的应用。