The Lyme disease spirochetes are a highly diverse group of bacteria with unique biological properties. Their ability to cycle between ticks and mammals requires that they adapt to variable and constantly changing environmental conditions. Outer surface protein C is an essential virulence determinant that has received considerable attention in vaccine and diagnostic assay development. Knowledge of OspC diversity, its antigenic determinants, and its production patterns throughout the enzootic cycle, as well as in the laboratory setting, is essential for understanding immune responses induced by infection or vaccination.

中文翻译：

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莱姆病螺旋体的多样性及其对感染和疫苗免疫反应的影响。

莱姆病螺旋体是一类高度多样化的细菌，具有独特的生物学特性。它们在tick和哺乳动物之间循环的能力要求它们适应不断变化的环境条件。外表面蛋白C是重要的毒力决定因素，在疫苗和诊断分析的开发中受到了极大的关注。了解OspC多样性，其抗原决定簇及其在整个动物园期间以及在实验室环境中的生产方式，对于了解由感染或疫苗接种引起的免疫反应至关重要。