Psoriasis, an autoimmune inflammatory disease, with its most common coexisting condition, psoriatic arthritis, seem to be more than just a local skin or joint disease, as evidence has accumulated over the years that it is associated with cardiovascular disease (CVD), which may confer an increased cardiovascular event and death rate. The data come mostly from observational studies and meta-analyses and indicate a potential pathogenetic link between these two systemic diseases, however definite proof of this detrimental relationship awaits further prospective studies. Newer anti-psoriatic biologic therapies seem to confer a cardiovascular benefit, but this needs future randomized controlled studies to confirm. All these intricate issues of a potential link between psoriasis and CVD are discussed and elaborated in this overview, in an attempt to shed further light on pivotal aspects of the association between psoriasis and CVD.

牛皮癣是一种自身免疫性炎性疾病，其最常见的并存状况是牛皮癣关节炎，似乎不仅仅是一种局部皮肤或关节疾病，因为多年来积累的证据表明它与心血管疾病（CVD）有关会增加心血管事件和死亡率。数据主要来自观察性研究和荟萃分析，表明这两种系统性疾病之间存在潜在的致病联系，但是这种有害关系的确切证据有待进一步的前瞻性研究。新型抗银屑病生物疗法似乎具有心血管益处，但这需要未来的随机对照研究来证实。本概述中讨论并详细阐述了牛皮癣与CVD之间潜在联系的所有这些复杂问题，