The rise in antimicrobial resistance (AMR) poses a major threat to animal agriculture and human health. To summarize and update current and emerging AMR issues that are significant for animal health and food safety, this issue presents a virtual AMR symposium consisting of seven review papers. These reviews cover a newly described AMR mechanism in Campylobacter, effects of AMR and microbiome on Campylobacter infection, plasmid-mediated colistin resistance in food-producing animals, the impact of point source or antibiotic residues on the environmental resistome, and potential factors influencing horizontal gene transfer in the intestines of food animals. These papers also identify significant knowledge gaps in AMR research and provide new directions for the development of innovative and effective strategies to mitigate AMR in the animal production system.

中文翻译：

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抗菌素耐药性：从基础科学到转化创新

抗菌素耐药性 (AMR) 的上升对畜牧业和人类健康构成重大威胁。为了总结和更新对动物健康和食品安全具有重要意义的当前和新出现的抗菌素耐药性问题，本期介绍了一个由七篇评论论文组成的虚拟抗菌素耐药性研讨会。这些评论涵盖了新描述的 AMR 机制弯曲杆菌, AMR 和微生物组对弯曲杆菌感染，食用动物中质粒介导的粘菌素抗性，点源或抗生素残留对环境抗性组的影响，以及影响食用动物肠道中水平基因转移的潜在因素。这些论文还确定了 AMR 研究中的重大知识差距，并为开发创新和有效的策略以减轻动物生产系统中的 AMR 提供了新的方向。