Ventricular assist devices (LVADs) are increasingly recognized for supporting blood circulation in heart failure patients who are non-transplant eligible. Because of its volume, the traditional pulsatile device is not easy to implant intracorporeally. Continuous flow LVADs (CF-LVADs) reduce arterial pulsatility and only offer continuous flow, which is different from physiological flow, and may cause long-term complications in the cardiovascular system. The aim of this study was to design a new pulsatile assist device that overcomes this disadvantage, and to test this device in the cardiovascular system. Firstly, the input and output characteristics of the new device were tested in a simple cardiovascular mock system. A detailed mathematical model was established by fitting the experimental data. Secondly, the model was tested in four pathological cases, and was simulated and coupled with a fifth-order cardiovascular system and a new device model using Matlab software. Using assistance of the new device, we demonstrated that the left ventricle pressure, aortic pressure, and aortic flow of heart failure patients improved to the levels of a healthy individual. Especially, in state IV level heart failure patients, the systolic blood pressure increased from 81.34 mmHg to 132.1 mmHg, whereas the diastolic blood pressure increased from 54.28 mmHg to 78.7 mmHg. Cardiac output increased from 3.21 L/min to 5.16 L/min. The newly-developed assist device not only provided a physiological flow that was similar to healthy individuals, but also effectively improved the ability of the pathological ventricular volume. Finally, the effects of the new device on other hemodynamic parameters are discussed.

心室辅助设备（LVAD）在支持不适合移植的心力衰竭患者中的​​血液循环方面得到越来越多的认可。由于其体积，传统的脉动装置不容易植入体内。连续血流LVAD（CF-LVAD）降低动脉搏动，仅提供连续血流，这与生理血流不同，并且可能导致心血管系统的长期并发症。这项研究的目的是设计一种克服这一缺点的新型搏动辅助设备，并在心血管系统中对其进行测试。首先，在简单的心血管模拟系统中测试了新设备的输入和输出特性。通过拟合实验数据建立了详细的数学模型。其次，该模型在4种病理情况下进行了测试，并使用Matlab软件对五阶心血管系统和新的设备模型进行了仿真和耦合。在新设备的帮助下，我们证明了心力衰竭患者的左心室压力，主动脉压力和主动脉血流可以改善到健康个体的水平。特别是在IV级心力衰竭患者中，收缩压从81.34 mmHg增加到132.1 mmHg，而舒张压从54.28 mmHg增加到78.7 mmHg。心输出量从3.21 L / min增加到5.16 L / min。新开发的辅助设备不仅提供了与健康个体相似的生理流程，而且还有效地提高了病理性心室容积的能力。最后，