Background: Biocompatible materials are used for treatment of blood circulatory system diseases, especially abdominal aortic aneurysms. The most popular and often used are knitted and polymer vascular patches. The aim of this study was to optimize the manufacturing process of implantable materials, ensuring antibacterial activity useful for treating abdominal aorta aneurysms. Methods: The vascular patch was manufactured from Trevira® yarn. The parameters of the intermediate product and vascular patch were tested according to standard procedures. Results: The vascular patch, manufactured from microsilver-containing yarn, with crimps on the surface of the patch, has been found useful for treatment of abdominal aorta aneurysms. Introducing crimps on the surface of the patch resulted in reduction of water permeability and enabled cutting of the graft at various angles without fraying at the cut ends of the biomaterial. The final vascular patch was marked by a gradual release of silver within 48 hours. Conclusions: On the basis of the performed test, it has been demonstrated that an implantable material for the treatment of abdominal aorta aneurysms was obtained, and that it can be considered as an alternative for currently used vascular patches. The final vascular patch was marked by a gradual release of silver during the first period of incubation. The antibacterial properties of the final product were confirmed by observation of a significant reduction in the number of Staphylococcus aureus and Klebsiella pneumoniae bacterial colonies.

中文翻译：

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腹主动脉瘤手术抗菌血管贴片结构与性能分析

背景：生物相容性材料用于治疗血液循环系统疾病，尤其是腹主动脉瘤。最流行和最常用的是针织和聚合物血管贴片。本研究的目的是优化可植入材料的制造工艺，确保抗菌活性可用于治疗腹主动脉瘤。方法：血管贴片由 Trevira® 纱线制成。根据标准程序测试中间产品和血管贴剂的参数。结果：血管贴片由含微银纱线制成，贴片表面有卷曲，已被发现可用于治疗腹主动脉瘤。在贴片表面引入卷曲导致透水性降低，并能够以各种角度切割移植物，而不会在生物材料的切割端磨损。最终的血管贴片以 48 小时内银的逐渐释放为标志。结论：在所进行的试验的基础上，已经证明获得了一种用于治疗腹主动脉瘤的可植入材料，可以考虑作为目前使用的血管补片的替代品。最终的血管贴片的标志是在第一个孵育期间银的逐渐释放。通过观察到金黄色葡萄球菌和肺炎克雷伯菌菌落数量显着减少，证实了最终产品的抗菌特性。