We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 286 Mexicans from the state of Sinaloa living in Culiacán (N = 103) and rural communities (N = 183) to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes for the state of Sinaloa include ten Native American most probable ancestry and five European most probable ancestry haplotypes. The admixture estimates revealed that the main genetic components in the state of Sinaloa are European (62.39 ± 3.47%) and Native American (37.61 ± 2.85%), while the African genetic component was estimated as virtually absent (0.00 ± 1.86%).

我们通过基于PCR-SSP的分型方法研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，来自居住在库利亚坎（N = 103）和农村社区的286名墨西哥人（N = 183），以获得有关等位基因和单倍型频率的信息。我们发现，锡那罗亚州最常见的单倍型包括十个美洲印第安人最可能的血统和五个欧洲最可能的血统。外加物的估计表明，锡那罗亚州的主要遗传成分是欧洲的（62.39±3.47％）和美洲原住民的（37.61±2.85％），而非洲的遗传成分估计几乎不存在（0.00±1.86％）。