We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 479 Mexicans from the state of Durango living in Durango city (N = 153) and rural communities (N = 326), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Durango include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in Durango are European (54.34 ± 1.68%) and Native American (45.66 ± 2.24%), while African genetic component was virtually absent (0.00 ± 2.03%). However, African haplotypes could be estimated at a proportion of 9.13%.

我们通过基于PCR-SSP的分型方法研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，来自居住在杜兰戈市（N = 153）和农村的杜兰戈州的479名墨西哥人社区（N = 326），以获得有关等位基因和单倍型频率的信息。我们发现在杜兰戈州发现的十个最常见的单体型包括八个美洲原住民和两个欧洲单体型。混合物估计显示，杜兰戈的主要遗传成分是欧洲（54.34±1.68％）和美洲原住民（45.66±2.24％），而非洲几乎没有遗传成分（0.00±2.03％）。但是，非洲单倍型的估计比例为9.13％。