We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 665 Mexicans from the state of Nuevo León living in the city of Monterrey (N = 226) and rural communities (N = 439), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Nuevo León include 12 Native American and three European haplotypes. Admixture estimates revealed that the main genetic components in the state of Nuevo León are Native American (54.53 ± 0.87% by ML; 48.88% of Native American haplotypes) and European (38.67 ± 4.06% by ML; 32.59% of European haplotypes), and a less prominent African genetic component (6.80 ± 4.30% by ML; 8.26% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因基于PCR-SSP的方法，对居住在蒙特雷（N = 226）和农村社区（N = 439）的新莱昂州的665名墨西哥人进行分类，以获得有关等位基因和单倍型频率的信息。我们发现，新莱昂州最常见的单体型包括12个美洲原住民和3个欧洲单体型。Admixture估计显示，新莱昂州的主要遗传成分是美洲原住民（按ML计算为54.53±0.87％；美国原住民单倍型为48.88％）和欧洲人（按ML计算为38.67±4.06％；欧洲单倍型为32.59％），以及不太突出的非洲遗传成分（按ML值计为6.80±4.30％；占非洲单倍型的8.26％）。