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Overview of diagnostic tools for Capripox virus infections.
Preventive Veterinary Medicine ( IF 2.6 ) Pub Date : 2019-05-28 , DOI: 10.1016/j.prevetmed.2019.104704
Andy Haegeman 1 , Annebel De Vleeschauwer 1 , Ilse De Leeuw 1 , Dejan Vidanović 2 , Milanko Šekler 2 , Tamaš Petrović 3 , Céline Demarez 1 , David Lefebvre 1 , Kris De Clercq 1
Affiliation  

Capripox viruses are the causative agents of important animal diseases in cattle (Lumpy Skin Disease), sheep (Sheeppox) and goats (Goatpox) with severe socio-economic impact in case of wide scale outbreaks. Therefore there is a constant need for adequate diagnostic tools. The assays must be fit-for-purpose to identify the virus quickly and correctly and to be useful for surveillance and monitoring at different stages of an epidemic. Different diagnostic performance characteristics are required depending on the situation and the test purpose. The need for high throughput, high specificity/sensitivity and the capability for differentiating field virus strains from vaccine strains drives the development of new and better assays preferably with an advantageous cost-benefit balance. This review aims to look at existing and new virological and serological diagnostic tools used in the control against diseases caused by Capripox viruses.

中文翻译:

Capripox病毒感染的诊断工具概述。

Capripox病毒是牛(大块头皮病),绵羊(Sheeppox)和山羊(Goatpox)中重要动物疾病的病原体,在大规模爆发时会严重影响社会经济。因此,始终需要适当的诊断工具。这些测定必须适合于目的,以快速,正确地识别病毒,并在流行的不同阶段用于监视和监视。根据情况和测试目的,需要不同的诊断性能特征。对高通量,高特异性/敏感性和将田间病毒株与疫苗株区分的能力的需求推动了新的和更好的测定的发展,优选具有有利的成本效益平衡。
更新日期:2019-05-28
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