Four new rearranged 6/6/5/6-fused lanostane-type triterpenoids, kadcoccitanes A–D (1–4), were isolated from the roots of Kadsura coccinea, and their structures were mainly elucidated by comprehensive analysis of their spectroscopic data. Additionally, the structure of 1 was ambiguously verified by single-crystal X-ray diffraction, while the structure of 2, which features a novel 8,16-epoxy motif, was validated by quantum chemical calculation of NMR parameters and ECD spectrum. Moreover, 1 and 4 were found to exhibited anticoagulant activity, while 3 and 4 were found to possess anti-platelet aggregation activity.

中文翻译：

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来自Kadsura coccinea根的四个具有6/6/5 / 6-Fused环系统的14（13→12）-Abeolanostane三萜类化合物。

四个新的重排6分之6/ 5/6稠合羊毛甾烷型三萜类化合物，kadcoccitanes A-d（1 - 4），从根分离南五味子红花，和它们的结构主要由它们的光谱数据的全面分析阐明。此外，通过单晶X射线衍射对1的结构进行了模棱两可的验证，而具有新颖的8,16-环氧基序的2的结构通过NMR参数和ECD光谱的量子化学计算得到了验证。此外，发现1和4具有抗凝活性，而3和4 被发现具有抗血小板聚集活性。