Introduction: Coeliac disease is a gluten-induced immune-mediated enteropathy, characterised by the expression of specific genotypes and the production of autoantibodies. The inflammatory process specifically targets the intestinal mucosa, but gastrointestinal and extraintestinal signs and symptoms can also be present. Non-coeliac gluten sensitivity (NCGS) can be diagnosed in individuals who have intestinal and/or extraintestinal symptoms related to the ingestion of gluten, but do not have autoantibodies and do not suffer from lesions in the duodenal mucosa. Among the extraintestinal manifestations, cutaneous manifestations are the most common for both diseases. Purpose: We conducted this review to illustrate the common and uncommon features underlying the association of coeliac disease and NCGS with cutaneous manifestations related to gluten ingestion. Areas covered: The roles of innate and adaptive immunity in the cutaneous appearance of gluten sensitivity will be discussed.

简介：腹腔疾病是一种由麸质诱导的免疫介导的肠病，其特征在于特定基因型的表达和自身抗体的产生。炎症过程专门针对肠粘膜，但也可能存在胃肠道和肠外体征和症状。非肠腔麸质敏感性（NCGS）可以诊断为具有与摄入麸质有关的肠道和/或肠道外症状，但没有自身抗体且没有十二指肠粘膜病变的个体。在肠外表现中，皮肤表现是两种疾病中最常见的。目的：我们进行了这项综述，以阐明乳糜泻和NCGS与与麸质摄入有关的皮肤表现相关的常见和不常见特征。涵盖的领域：将讨论先天性和适应性免疫在面筋敏感性皮肤外观中的作用。