Background: Children with cerebral palsy (CP) show age-driven development and individual fluctuations in walking capacity. Aim: 1. To precisely quantify 1MWT changes in children with CP, GMFCS level 1 and 2, generating 1MWT percentiles, depicting expected development over 6 months; 2. to assess the effect of a 6-month rehabilitation using whole-body vibration (WBV). Methods: Retrospective data analysis in 210 children with CP, GMFCS 1 and 2 who received standardized rehabilitation (DRKS00011331). 1MWT was assessed before (M0) and after treatment (M6), and at a 6-month follow-up (M12). Centiles were created using the lambda-mu-sigma method. Cohen's d was used to assess effect size. Results: We created 1MWT percentiles using data of all 210 children (M0 data). A small treatment effect size (d = 0.46) was found (M6 and M12 data). Conclusions: Using the generated centiles clinicians may monitor 1MWT changes over 6 months. Combining WBV and conventional physiotherapy may improve 1MWT in children with CP. Abbreviations: 1MWT: One-Minute Walk Test; 6MWT: Six-Minute Walk Test; CP: Cerebral palsy; ES: effect size; GMFCS: Gross Motor Function Classification System; GMFM-66: Gross Motor Function Measure 66; LOESS: Locally Estimated Scatterplot Smoothing; LMS: lambda-mu-sigma; SD: standard deviation; WBV: whole-body-vibration.

中文翻译：

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脑性瘫痪GMFCS 1级和2级儿童的一分钟步行测试，用于识别康复后的治疗效果的参考值。

背景：脑性瘫痪（CP）儿童表现出年龄驱动的发育和步行能力的个体波动。目的：1.精确量化患有CP，GMFCS 1级和2级儿童的1MWT变化，产生1MWT百分位，描绘6个月的预期发展；2.使用全身振动（WBV）评估六个月康复的效果。方法：回顾性分析210例接受标准化康复治疗的CP，GMFCS 1和2的儿童（DRKS00011331）。在治疗前（M0）和治疗后（M6）以及6个月的随访（M12）评估了1MWT。使用lambda-mu-sigma方法创建分数。Cohen d用于评估效应量。结果：我们使用所有210个孩子的数据（M0数据）创建了1MWT百分位数。发现较小的治疗效果大小（d = 0.46）（M6和M12数据）。结论：使用生成的百分位数，临床医生可以监视6个月内1MWT的变化。WBV与常规理疗相结合可改善CP儿童的1MWT。缩写：1MWT：一分钟步行测试；6MWT：六分钟步行测试；CP：脑瘫；ES：效果大小；GMFCS：运动功能总分类系统；GMFM-66：运动功能总测值66；黄土：局部估计散点图平滑；LMS：lambda-mu-sigma；SD：标准偏差；WBV：全身振动。局部估计的散点图平滑；LMS：lambda-mu-sigma；SD：标准偏差；WBV：全身振动。局部估计的散点图平滑；LMS：lambda-mu-sigma；SD：标准偏差；WBV：全身振动。