We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 439 Mexicans from the state of Sonora living in Ciudad Obregón (N = 143), Hermosillo (N = 99), and rural communities (N = 197) to obtain information regarding allelic and haplotypic frequencies. We find that the 13 most frequent haplotypes for the state of Sonora include nine Native American, three European and one Asian haplotypes. Admixture estimates revealed that the main genetic components in the state of Sonora are European (51.25 ± 2.90% by ML; 37.70% of European haplotypes) and Native American (43.35 ± 2.57% by ML; 39.64% of Native American haplotypes), while the African genetic component was less apparent (5.39 ± 2.54% by ML; 11.04% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因基于PCR-SSP的方法，在居住在奥布雷贡城（N = 143），埃莫西约（N = 99）和农村社区（N = 197）的索诺拉州的439名墨西哥人中获得有关等位基因和单倍型频率的信息。我们发现，索诺拉州的13种最常见单倍型包括9种美洲原住民，3种欧洲单倍型和一种亚洲单倍型。外加剂的估计表明，索诺拉州的主要遗传成分是欧洲的（按ML分类为51.25±2.90％；欧洲的单倍型为37.70％）和美洲原住民的（按ML分类的为43.35±2.57％；美国原住民的39.64％）。非洲遗传成分不太明显（按ML值，为5.39±2.54％；非洲单倍型的11.04％）。