We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 2046 Mexicans from the state of Jalisco living in the city of Guadalajara (N = 1189), Tlajomulco (N = 30), Tlaquepaque (N = 39), Tonalá (N = 35), Zapopan (N = 168) and rural communities (N = 585), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes found in the state of Jalisco include nine Native American most probable ancestry and three European haplotypes. Admixture estimates revealed that the main genetic components in the state of Jalisco are European (48.45 ± 1.18% by ML; 41.66% of European haplotypes) and Native American (44.02 ± 1.24% by ML; 39.86% of Native American haplotypes), while African genetic component is less apparent (7.53 ± 0.30% by ML; 9.62% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）基于PCR-SSP的等位基因，来自居住在瓜达拉哈拉（N = 1189），Tlajomulco（N = 30），Tlaquepaque（N = 39），Tonalá（N = 35），扎波潘（Zapopan）的哈利斯科州的2046年墨西哥人（N = 168）和农村社区（N = 585），以获得有关等位基因和单倍型频率的信息。我们发现，在哈利斯科州发现的最常见单倍型包括九个美国原住民最可能的血统和三个欧洲单倍型。外加剂估计显示，哈利斯科州的主要遗传成分是欧洲（按ML分类为48.45±1.18％；欧洲单倍型的41.66％）和美国原住民（按ML分类为44.02±1.24％；为美国原住民的39.86％），而非洲人遗传成分不太明显（按ML值，为7.53±0.30％；非洲单倍型的9.62％）。