We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 95 Mexicans from the state of Aguascalientes to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes in the state of Aguascalientes include four Native American, three European and one Asian haplotypes. Admixture estimates revealed that the main genetic components in the state of Aguascalientes are Native American (54.53 ± 3.22% by ML; 44.21% of Native American haplotypes) and European (44.34 ± 0.45% by ML; 40.53% of European haplotypes), and a relatively low African genetic component (1.13 ± 2.33% by ML; 5.26% of African haplotypes).

我们通过基于PCR-SSP的方法对来自Aguascalientes州的95名墨西哥人进行了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因研究，以获得有关等位基因和单倍型频率及其连锁的信息不平衡。我们发现，阿瓜斯卡连特斯州最常见的单倍型包括四种美洲原住民，三种欧洲单倍型和一种亚洲单倍型。外加剂估计显示，阿瓜斯卡连特斯州的主要遗传成分是美洲原住民（按ML分类为54.53±3.22％；美国原住民单倍型为44.21％）和欧洲（按ML分类为44.34±0.45％；欧洲单倍型为40.53％），以及相对较低的非洲遗传成分（按ML测得1.13±2.33％；非洲单倍型的5.26％）。