We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in the state of Guerrero are Native American (61.36 ± 2.69% by ML; 54.17% of Native American haplotypes) and European (35.01 ± 4.59% by ML; 32.29% of European haplotypes), and a relatively low African genetic component (3.63 ± 2.38% by ML; 5.90% of African haplotypes).

我们通过基于PCR-SSP的研究从Guerrero州的144名墨西哥人中研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）等位基因，以获得有关等位基因和单倍型频率的信息。我们发现，格雷罗州十种最常见的单体型包括八种美洲原住民和两种欧洲单体型。外加剂的估计表明，格雷罗州的主要遗传成分是美洲原住民（按ML分类为61.36±2.69％；美国原住民单倍型为54.17％）和欧洲（按ML分类为35.01±4.59％；欧洲单倍型为32.29％），以及相对较低的非洲遗传成分（按遗传学分析为3.63±2.38％；非洲单倍型的5.90％）。