This review compares droplet-based microfluidic systems used to study crystallization fundamentals in chemistry and biology. An original high-throughput droplet-based microfluidic platform is presented. It uses nanoliter droplets, generates a chemical library, and directly solubilizes powder, thus economizing both material and time. It is compatible with all solvents without the need for surfactant. Its flexibility permits phase diagram determination and crystallization studies (screening and optimizing experiments) and makes it easy to use for nonspecialists in microfluidics. Moreover, it allows concentration measurement via ultraviolet spectroscopy and solid characterization via X-ray diffraction analysis.

中文翻译：

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使用微流控技术研究结晶基础的进展。

本文对基于液滴的微流体系统进行了比较，该系统用于研究化学和生物学中的结晶基础。提出了一种原始的基于高通量液滴的微流体平台。它使用纳升液滴，生成化学文库，并直接溶解粉末，从而节省了材料和时间。无需表面活性剂即可与所有溶剂兼容。它的灵活性允许进行相图确定和结晶研究（筛选和优化实验），并使其易于在非微流体领域使用。此外，它允许通过紫外光谱进行浓度测量，并通过X射线衍射分析进行固体表征。