Mycotoxins are a significant food safety concern. Aflatoxins, trichothecenes, fumonisins, and ochratoxin A are considered the most important mycotoxins due to their frequent occurrence in food products and their well-known toxicity. The regulation of mycotoxin biosynthesis occurs mainly at transcriptional level, and specific regulators have been described in every biosynthetic cluster. Secondary metabolite production, including mycotoxin synthesis, is also regulated by general regulator pathways affected by light, osmotic stress and oxidative stress, among others. This review is focused on this genetic regulation of mycotoxin biosynthesis by specific genes and global regulators.

中文翻译：

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黄曲霉毒素，曲霉毒素A，单端孢菌素和伏马毒素的生物合成的遗传调控：综述。

霉菌毒素是重要的食品安全问题。黄曲霉毒素，曲霉毒素，伏马毒素和and曲霉毒素A被认为是最重要的霉菌毒素，因为它们经常出现在食品中，并且具有众所周知的毒性。霉菌毒素生物合成的调节主要发生在转录水平，并且在每个生物合成簇中都描述了特定的调节剂。次生代谢产物的产生，包括霉菌毒素的合成，也受到受光，渗透压和氧化应激等影响的一般调节剂途径的调节。这项审查的重点是特定基因和全球监管机构对霉菌毒素生物合成的遗传调控。