Acute iron poisoning and chronic iron overload consequences in significant morbidity and mortality worldwide. Treatment of acute iron poisoning and chronic iron overload can be challenging and care providers are often tackled with management dilemmas. Iron chelating agents are commonly prescribed for patients with iron deficiency anemia. In this review article, different analytical techniques are reported used for qualitative and quantitative analysis of iron chelating agents like, deferiprone, deferoxamine, and deferasirox. Efforts are taken to collect all related articles published till October 2018. This review discusses all analytical methods, its advantages and disadvantages as well as its applications. This article will help you to know about basic analytical techniques as well as advanced hyphenated techniques practiced for determination of iron chelating agents in different matrices. The techniques discussed in this review follow the ICH guidelines for method validation.

中文翻译：

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分析方法测定铁螯合剂：综述。

急性铁中毒和慢性铁超载导致全世界范围内大量发病和死亡。急性铁中毒和慢性铁超负荷的治疗可能具有挑战性，护理人员通常会遇到管理难题。铁螯合剂通常用于缺铁性贫血患者。在这篇综述文章中，报道了用于铁螯合剂（如去铁酮，去铁胺和去铁胺）的定性和定量分析的不同分析技术。努力收集到2018年10月为止发布的所有相关文章。此评论讨论了所有分析方法，其优缺点以及其应用。本文将帮助您了解用于确定不同基质中铁螯合剂的基本分析技术以及高级联用技术。本文中讨论的技术遵循ICH指南进行方法验证。