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Natural Products for the Treatment of Neurodegenerative Diseases.
Current Medicinal Chemistry ( IF 3.5 ) Pub Date : 2020-09-30 , DOI: 10.2174/0929867326666190527120614
Ze Wang 1, 2 , Chunyang He 1, 2 , Jing-Shan Shi 1
Affiliation  

Neurodegenerative diseases are a heterogeneous group of disorders characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Alzheimer's Disease (AD), Parkinson's Disease (PD) and Spinal Cord Injury (SCI) are the common neurodegenerative diseases, which typically occur in people over the age of 60. With the rapid development of an aged society, over 60 million people worldwide are suffering from these uncurable diseases. Therefore, the search for new drugs and therapeutic methods has become an increasingly important research topic. Natural products especially those from the Traditional Chinese Medicines (TCMs), are the most important sources of drugs, and have received extensive interest among pharmacist. In this review, in order to facilitate further chemical modification of those useful natural products by pharmacists, we will bring together recent studies in single natural compound from TCMs with neuroprotective effect.



中文翻译:

用于治疗神经退行性疾病的天然产品。

神经变性疾病是一组异质性疾病,其特征在于中枢神经系统或周围神经系统的结构和功能的逐步退化。阿尔茨海默氏病(AD),帕金森氏病(PD)和脊髓损伤(SCI)是常见的神经退行性疾病,通常发生在60岁以上的人群中。随着老龄化社会的迅速发展,全世界有超过6000万人患有这些无法治愈的疾病。因此,寻找新药和治疗方法已成为越来越重要的研究课题。天然产品,尤其是中药(TCM)的天然产品,是最重要的药物来源,在药剂师中引起了广泛的兴趣。在这篇评论中

更新日期:2020-10-12
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