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Power-frequency magnetic fields at 50 Hz do not affect fertility and development in rats and mice
Electromagnetic Biology and Medicine ( IF 1.6 ) Pub Date : 2018-11-14 , DOI: 10.1080/15368378.2018.1545664
Guoran Ruan 1, 2 , Xingfa Liu 3 , Yemao Zhang 3 , Baoquan Wan 3 , Jiangong Zhang 3 , Jinsheng Lai 1 , Mengying He 1 , Chen Chen 1
Affiliation  

ABSTRACT In the present study, the effects of power-frequency magnetic fields (PF-MF) on fertility and development were investigated in rats and mice. Adult Sprague-Dawley rats and C57BL/6J mice were divided into four groups: a sham exposure group and 30-µT, 100-µT and 500-µT PF-MF exposure groups. The rats were exposed for 24 weeks, and the exposure time for mice ranged from 18 d to 12 weeks, dependent on the different investigated end points. The rats and mice were exposed for 20 h/d. Plasma hormone levels in rats and mice were analyzed. Furthermore, pregnancy rates and implanted embryos were recorded in pregnant mice. Finally, the neonatal growth of mice was evaluated. The results showed that none of the three intensities affected the body weight and paired ovary weight in female rats. Meanwhile, none of the three intensities affected the body weight, weights of paired testes, weights of paired epididymis and sperm count in male rats. Similarly, no significant differences were found in plasma sex hormone levels between the different PF-MF exposure groups and the sham exposure group. In addition, the pregnancy rates and implanted embryos were not significantly different between the four groups. Moreover, PF-MF exposures had no effects on either the number of fetuses in pregnant mice or the growth and development of neonatal mice.

中文翻译:

50 Hz 的工频磁场不影响大鼠和小鼠的生育能力和发育

摘要 在本研究中,在大鼠和小鼠中研究了工频磁场 (PF-MF) 对生育和发育的影响。成年 Sprague-Dawley 大鼠和 C57BL/6J 小鼠分为四组:假暴露组和 30-µT、100-µT 和 500-µT PF-MF 暴露组。大鼠暴露 24 周,小鼠暴露时间从 18 天到 12 周不等,这取决于不同的研究终点。大鼠和小鼠暴露20小时/天。分析了大鼠和小鼠的血浆激素水平。此外,在怀孕小鼠中记录了怀孕率和植入的胚胎。最后,评估小鼠的新生儿生长。结果表明,三种强度均不影响雌性大鼠的体重和配对卵巢重量。同时,三种强度均不影响雄性大鼠的体重、配对睾丸重量、配对附睾重量和精子数量。同样,在不同 PF-MF 暴露组和假暴露组之间,血浆性激素水平也没有发现显着差异。此外,四组之间的妊娠率和植入胚胎没有显着差异。此外,PF-MF 暴露对怀孕小鼠的胎儿数量或新生小鼠的生长发育没有影响。四组之间的妊娠率和植入胚胎没有显着差异。此外,PF-MF 暴露对怀孕小鼠的胎儿数量或新生小鼠的生长发育没有影响。四组之间的妊娠率和植入胚胎没有显着差异。此外,PF-MF 暴露对怀孕小鼠的胎儿数量或新生小鼠的生长发育没有影响。
更新日期:2018-11-14
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