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Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV/AIDS.
AIDS Reviews ( IF 1.9 ) Pub Date : 2018-12-15 , DOI: 10.24875/aidsrev.18000034
Vicente Soriano 1, 2 , Jorge Del Romero 3
Affiliation  

Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Recent epidemics and outbreaks of STIs among men having sex with men reflect the global loss of fear to HIV/AIDS. The -alarming rising rates of STIs worldwide have been fueled by: (1) rapid spread of drug resistance, that is, for Neisseria gonorrhoeae and Mycoplasma genitalium; (2) unprecedented impact of recreational drugs (chemsex) and internet (apps, websites) for facilitating exposure to multiple sex partners; and (3) growing rates of sexual violence and commercial sex, associated with wars, refugees, migrations, traveling, and sexual tourism. Moreover, there is an increasing appreciation of sexual transmission for other agents, -including human T-lymphotropic virus type 1, hepatitis A and C viruses, Zika, and Ebola. For addressing this new scenario for STIs, an expert panel workshop was arranged in Madrid, Spain in May 2018. This review summarizes the discussions at the meeting.

中文翻译:

抗逆转录病毒药物治疗艾滋病毒/艾滋病成功后,性传播感染反弹。

每天有将近100万人感染四种主要可治愈的性传播感染(STIs),即滴虫,衣原体,淋病和梅毒。尽管全球发生率很高,但性传播感染仍然是被忽视的疾病。抗逆转录病毒药物成功阻止艾滋病毒感染者发展为艾滋病的进程以及阻止艾滋病毒通过暴露前或暴露后预防而传播给未感染的接触者,必须通过风险补偿来增加具有风险的性行为。与男人发生性关系的男子中最近发生的性传播感染和性传播疾病暴发反映了全球对艾滋病毒/艾滋病的恐惧已消失。全世界范围内令人震惊的性传播感染率上升是由以下因素推动的:(1)耐药性的快速传播,即淋病奈瑟氏球菌和生殖器支原体;(2)休闲药物(chemsex)和互联网(应用程序,网站)对促进接触多个性伴侣的影响空前;(3)与战争,难民,移民,旅行和性旅游相关的性暴力和商业性行为的发生率不断上升。此外,人们对其他媒介的性传播越来越重视,这些媒介包括人类1型T淋巴细胞病毒,甲型和丙型肝炎病毒,寨卡病毒和埃博拉病毒。为了应对这种新的性传播感染方案,2018年5月在西班牙马德里组织了一次专家小组讲习班。这次审查总结了会议的讨论情况。对其他媒介的性传播越来越重视,包括-人类T型淋巴病毒1型,甲型和丙型病毒,寨卡病毒和埃博拉病毒。为了应对这种新的性传播感染方案,2018年5月在西班牙马德里组织了一次专家小组讲习班。这次审查总结了会议的讨论情况。对其他媒介的性传播越来越重视,包括-人类T型淋巴病毒1型,甲型和丙型病毒,寨卡病毒和埃博拉病毒。为了应对这种新的性传播感染方案,2018年5月在西班牙马德里组织了一次专家小组讲习班。这次审查总结了会议的讨论情况。
更新日期:2020-08-21
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