This review will first recall the phenomena of "cortical inheritance" observed and genetically demonstrated in Paramecium 40 years ago, and later in other ciliates (Tetrahymena, Oxytricha, Paraurostyla), and will analyze the deduced concept of "cytotaxis" or "structural memory." The significance of these phenomena, all related (but not strictly restricted) to the properties of ciliary basal bodies and their mode of duplication, will be interpreted in the light of present knowledge on the mechanism and control of basal body/centriole duplication. Then other phenomena described in a variety of organisms will be analyzed or mentioned which show the relevance of the concept of cytotaxis to other cellular processes, mainly (1) cytoskeleton assembly and organization with examples on ciliates, trypanosome, mammalian cells and plants, and (2) transmission of polarities with examples on yeast, trypanosome and metazoa. Finally, I will discuss some aspects of this particular type of non-DNA inheritance: (1) why so few documented examples if structural memory is a basic parameter in cell heredity, and (2) how are these phenomena (which all rely on protein/protein interactions, and imply a formatting role of preexisting proteinic complexes on neo-formed proteins and their assembly) related to prions?

中文翻译：

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预先形成的细胞结构和细胞遗传。

这篇综述将首先回顾 40 年前在草履虫中观察到和遗传证明的“皮层遗传”现象，然后在其他纤毛虫（四膜虫、Oxytrica、Paraurostyla）中，并将分析推导出的“细胞趋化”或“结构记忆”概念。 ” 这些现象的意义，都与睫状基体的特性及其复制模式有关（但不严格限制），将根据关于基体/中心粒复制的机制和控制的现有知识来解释。然后将分析或提及在各种生物体中描述的其他现象，这些现象表明细胞趋化的概念与其他细胞过程的相关性，主要是 (1) 细胞骨架组装和组织，例如纤毛虫、锥虫、哺乳动物细胞和植物，以及 (2) 以酵母、锥虫和后生动物为例的极性传递。最后，我将讨论这种特殊类型的非 DNA 遗传的某些方面：（1）如果结构记忆是细胞遗传的基本参数，那么为什么很少有文献记载的例子，以及（2）这些现象（它们都依赖于蛋白质）如何？ /蛋白质相互作用，并暗示与朊病毒相关的新形成蛋白质及其组装上预先存在的蛋白质复合物的格式化作用？