当前位置: X-MOL 学术Hum. Reprod. Update › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Gestational surrogacy.
Human Reproduction Update ( IF 14.8 ) Pub Date : 2003-12-03 , DOI: 10.1093/humupd/dmg033
Peter R Brinsden 1
Affiliation  

Gestational surrogacy is a treatment option available to women with certain clearly defined medical problems, usually an absent uterus, to help them have their own genetic children. IVF allows the creation of embryos from the gametes of the commissioning couple and subsequent transfer of these embryos to the uterus of a surrogate host. The indications for treatment include absent uterus, recurrent miscarriage, repeated failure of IVF and certain medical conditions. Treatment by gestational surrogacy is straightforward and follows routine IVF procedures for the commissioning mother, with the transfer of fresh or frozen-thawed embryos to the surrogate host. The results of treatment are good, as would be expected from the transfer of embryos derived from young women and transferred to fit, fertile women who are also young. Clinical pregnancy rates achieved in large series are up to 40% per transfer and series have reported 60% of hosts achieving live births. The majority of ethical or legal problems that have arisen out of surrogacy have been from natural or partial surrogacy arrangements. The experience of gestational surrogacy has been largely complication-free and early results of the follow-up of children, commissioning couples and surrogates are reassuring. In conclusion, gestational surrogacy arrangements are carried out in a few European countries and in the USA. The results of treatment are satisfactory and the incidence of major ethical or legal complications has been limited. IVF surrogacy is therefore a successful treatment for a small group of women who would otherwise not be able to have their own genetic children.

中文翻译:

代孕。

妊娠代孕是具有一定明确医学问题(通常是子宫缺失)的妇女的一种治疗选择,以帮助她们生育自己的遗传子女。IVF允许从调试夫妇的配子中产生胚胎,然后将这些胚胎转移到代孕宿主的子宫中。治疗的适应症包括子宫缺失,反复流产,IVF反复失败和某些医疗状况。妊娠代孕的治疗很简单,并且对母亲进行常规的IVF程序,将新鲜或冻融的胚胎转移到代孕宿主。正如从年轻妇女获得的胚胎转移到也年轻的健康,可育妇女的胚胎移植所预期的那样,治疗效果良好。大规模转诊的临床妊娠率高达每次转移40%,并且已报告60%的宿主实现了活产。由代孕产生的大多数道德或法律问题都来自自然或部分代孕安排。妊娠代孕的经验在很大程度上没有并发症,而且对儿童,委托夫妇和代孕母亲的随访的早期结果令人放心。总之,在几个欧洲国家和美国进行了代孕安排。治疗结果令人满意,并且重大伦理或法律并发症的发生率受到限制。因此,试管婴儿代孕是一小部分妇女的成功疗法,否则他们将无法拥有自己的遗传子女。
更新日期:2019-11-01
down
wechat
bug