The number of indwelling medical devices is escalating, and an increasing proportion of device-related infections are being caused by Candida spp. Candida spp. produce biofilms on synthetic materials, which facilitates adhesion of the organisms to devices and renders them relatively refractory to medical therapy. Management of device-related Candida infections can be challenging. Removal of the infected device is generally needed to establish cure of Candida infections of medical devices. However, since the pathogenesis of Candida bloodstream infection is complicated, more studies are necessary to determine the role of catheter exchange in patients with both gastrointestinal tract mucositis and indwelling catheters. The medical and economic impact of these infections is enormous.

中文翻译：

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医疗器械念珠菌感染。

留置医疗设备的数量在增加，由假丝酵母菌引起的与设备相关的感染也越来越多。念珠菌属 在合成材料上产生生物膜，这有助于将生物粘附到设备上，并使它们相对难于医学治疗。与设备相关的念珠菌感染的管理可能具有挑战性。通常需要移除受感染的设备才能建立医疗设备念珠菌感染的治疗方法。但是，由于念珠菌血流感染的发病机理复杂，因此需要进行更多的研究来确定在胃肠道粘膜炎和留置导管患者中更换导管的作用。这些感染的医学和经济影响是巨大的。