Abstract: Child maltreatment is associated with increased risk of substance abuse in adulthood. However, prior investigations have not examined substance use specifically in pregnancy and have relied on self-report of substance use. The present study addresses these gaps via secondary analysis of 295 primarily low-income, Black postpartum women who agreed to complete a brief questionnaire and subsequently provided urine and hair samples. A clear relationship emerged between self-reported maltreatment and positive toxicology (with drug use present in 37.2% of maltreated participants and 17.1% of nonmaltreated participants; p < .001). Depression and violence exposure were positively associated with maltreatment and with drug use. The combined effect of violence exposure and depression mediated the association between maltreatment and drug use during pregnancy. (The bootstrapped 95% confidence interval of total indirect effect ranged .14–.80.) This investigation is the first to show an association between childhood maltreatment and toxicological evidence of drug use in pregnancy.

中文翻译：

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在儿童期虐待与怀孕期间吸毒之间进行调解员的生态发展探索。

摘要：虐待儿童与成年后滥用药物的风险增加有关。但是，先前的调查并未专门检查怀孕期间的药物使用情况，而是依靠药物使用情况的自我报告。本研究通过对295名主要是低收入，黑人产后妇女的二级分析来解决这些差距，这些妇女同意填写一份简短的调查表，随后提供尿液和头发样本。自我报告的虐待与阳性毒理学之间存在明确的关系（在37.2％的虐待患者和17.1％的未虐待参与者中使用药物； p <.001）。抑郁和暴力暴露与虐待和吸毒成正相关。暴力暴露和抑郁症的综合作用介导了怀孕期间虐待和药物滥用之间的联系。（自举的95％的总间接作用置信区间为.14-.80。）这项研究是首次显示儿童期虐待与妊娠期吸毒的毒理学证据之间的关联。