Left and inconsistent hand preferences are the markers of atypical brain organization that relate with cognitive and behavioural traits as well as with developmental disorders, whereas intolerance of uncertainty is the trait of inability to bear future uncertainty that mediates anxiety disorders and depression. In the present study, relationship of hand preference with intolerance of uncertainty was studied in a sample of 862 college students (age: M = 21.4 years, SD = 3.12). Results show that left-handers had lower prospective intolerance of uncertainty than right-handers. Furthermore, inconsistent right-handers had lower inhibitive intolerance of uncertainty than consistent right-handers. Thus, the present study supports the likelihood that atypical brain organization advantages tolerance of uncertainty (i.e., lower intolerance of uncertainty). Implications of these findings for understanding the contribution of intolerance of uncertainty to anxiety have been discussed.

中文翻译：

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手的偏爱和不确定性的不宽容：非典型的大脑偏侧化优势降低了不确定性的不宽容度。

左手和不一致的手部偏好是与认知和行为特征以及发育障碍相关的非典型大脑组织的标志，而不确定性的不宽容则是无法承受未来不确定性的特征，这种不确定性会介导焦虑症和抑郁症。在本研究中，在862名大学生（年龄：M = 21.4岁，SD = 3.12）中对手偏爱与不确定性的不耐受之间的关系进行了研究。结果表明，左撇子的不确定性比右撇子的预期容忍度低。此外，不一致的右撇子比一致的右撇子具有更低的不确定性抑制不宽容度。因此，本研究支持非典型大脑组织有利于不确定性容忍（即较低的不确定性不容忍）的可能性。