Institutional Animal Care and Use Committees (IACUCs) occasionally face regulatory requirements for which clear guidance may not be available. Either the regulating body has chosen not to provide such guidance or the guidance may be minimal or even ambiguous. Such guidance may be desirable when institutions have research needs, in which case IACUCs are left to their own interpretation to develop internal policies, procedures, and documents. Typically, this is approached by an IACUC working with partners in the laboratory animal community and may involve input from regulators who can provide context as well as parameters to consider. Over time, shared institutional experiences and documentation coalesce to create a general framework that provides a baseline for others to consider as templates for further policy elaboration or development. The strength of this approach relies on the ability to share freely, including having unobstructed access to such documents.

中文翻译：

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IACUC在缺乏监管指导的情况下的作用。

机构动物护理和使用委员会（IACUC）有时会遇到监管要求，而这些要求可能没有明确的指导。调节机构选择不提供这种指导，或者该指导可能是最小的，甚至是模棱两可的。当机构有研究需要时，可能需要此类指导，在这种情况下，IACUC由他们自己解释以制定内部政策，程序和文件。通常，这是由IACUC与实验动物界的合作伙伴合作进行的，可能涉及监管机构的意见，监管机构可以提供要考虑的背景信息和参数。随着时间的流逝，共享的机构经验和文档会结合起来，创建一个通用框架，为其他人提供一个基准，以作为进一步制定或制定政策的模板。