Myelodysplastic syndromes (MDS) are a challenging group of diseases for clinicians and researchers, as both disease course and pathobiology are highly heterogeneous. In (suspected) MDS patients, multi-parameter flow cytometry can aid in establishing diagnosis, risk stratification and choice of therapy. This review addresses the developments and future directions of multi-parameter flow cytometry scores in MDS. Additionally, we propose an integrated diagnostic algorithm for suspected MDS.

中文翻译：

---

多参数流式细胞术在骨髓增生异常综合征中的临床意义

骨髓增生异常综合征 (MDS) 是临床医生和研究人员面临的一组具有挑战性的疾病，因为病程和病理生物学都具有高度异质性。在（疑似）MDS 患者中，多参数流式细胞术可以帮助建立诊断、风险分层和治疗选择。本综述讨论了 MDS 中多参数流式细胞术评分的发展和未来方向。此外，我们提出了一种针对疑似 MDS 的综合诊断算法。