Three-dimensional (3D) printing holds tremendous potential as a tool for patient-specific devices. This proof-of- concept study demonstrated the feasibility, antimicrobial properties, and computed tomography(CT) imaging characteristics of iodine/polyvinyl alcohol (PVA) 3D meshes and stents. Under scanning electron microscopy, cross-linked PVA displays smoother and more compacted filament arrangements. X-ray and transaxial CT images of iodized PVA vascular stents show excellent visibility and significantly higher Hounsfield units of radiopacity than control prints. Three-dimensional PVA prints stabilized by glutaraldehyde cross-linking and loaded with iodine through sublimation significantly suppressed Escherichia coli and Staphylococcus aureus growth in human blood agar disk diffusion assays. It is suggested that PVA 3D printing with iodine represents an important new synthetic platform for generating a wide variety of antimicrobial and high-visibility devices.

中文翻译：

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三维印刷抗菌和不透射线构造。

三维（3D）打印作为针对特定患者的设备的工具具有巨大的潜力。这项概念验证研究证明了碘/聚乙烯醇（PVA）3D网格和支架的可行性，抗菌性能和计算机断层扫描（CT）成像特性。在扫描电子显微镜下，交联的PVA显示出更平滑，更紧凑的灯丝排列。碘化PVA血管支架的X射线和经轴CT图像显示出卓越的可见性，并且Hounsfield单位的射线不透性明显高于对照照片。戊二醛交联稳定并通过升华负载碘的三维PVA印迹在人血琼脂盘扩散测定中显着抑制了大肠杆菌和金黄色葡萄球菌的生长。