BACKGROUND Patient-reported outcomes (PROs) are information provided directly by patients that helps in improving patient diagnosis and treatment. Validated translations of PROs can be used to treat international patients. Electronic systems and especially mobile devices provide a great opportunity for their collection; however, these systems are normally study-oriented and therefore single language, not scalable, and not interoperable. OBJECTIVES This article reports the development of a multicenter, multilingual, and interoperable electronic PRO (ePRO) system and evaluates its user satisfaction in an international clinical study. METHODS The ePRO named "MoPat2" was developed using Java 8 and jQuery Mobile 1.4.5. The system was evaluated in the context of the European dermatology project "European Network on Assessment of Severity and Burden of Pruritus"(PruNet), which aimed to unify the assessment of itch in routine dermatological care in Europe. Twenty-six clinicians and 468 patients from 8 European clinical centers were asked to complete a user satisfaction questionnaire regarding the use of MoPat2 with a tablet personal computer. The results were then analyzed and correlated with the age, gender, and language of the respondents. RESULTS MoPat2 was enhanced with multilingual capabilities and is now able to conduct surveys in several languages, as well as store and display the results in the local language. The interviewed clinicians rated the system with an average score of 2.0 ("good") in a 1 to 5 Likert scale. Note that 93.9% of the patients (439 of 468) reported having got on well using the system and 88.9% (416 of 456) would be willing to further use it. The age of the patients not willing to further use MoPat2 was, in average, considerably higher than the age of patients willing to use the system. CONCLUSIONS This study represents the first use of an ePRO system for the collection of multilingual PROs in an international, multicenter setting. MoPat2 has been evaluated by both clinicians and patients in the context of a European dermatological study, resulting in a high user satisfaction. The system will be further developed to include new features such as patient follow-ups outside of the clinical setting.

中文翻译：

---

欧洲范围内多语种患者报告结果的电子馆藏。

背景技术患者报告的结局（PRO）是由患者直接提供的有助于改善患者诊断和治疗的信息。经验证的PRO译文可用于治疗国际患者。电子系统，尤其是移动设备为收集它们提供了很大的机会；但是，这些系统通常是面向学习的，因此是单一语言，不可扩展，并且不能互操作。目的本文报告了多中心，多语言和可互操作的电子PRO（ePRO）系统的开发，并在一项国际临床研究中评估了其用户满意度。方法使用Java 8和jQuery Mobile 1.4.5开发了名为“ MoPat2”的ePRO。该系统是在欧洲皮肤病学项目“ 9％（456个中的416个）愿意进一步使用它。平均而言，不愿意进一步使用MoPat2的患者年龄要比愿意使用该系统的患者年龄高得多。结论本研究代表了在国际，多中心环境中首次使用ePRO系统来收集多语言PRO。MoPat2已在欧洲皮肤病学研究中由临床医生和患者进行了评估，从而获得了很高的用户满意度。该系统将得到进一步开发，以包括新功能，例如临床环境之外的患者随访。结论本研究代表了在国际，多中心环境中首次使用ePRO系统来收集多语言PRO。MoPat2已在欧洲皮肤病学研究中由临床医生和患者进行了评估，从而获得了很高的用户满意度。该系统将得到进一步开发，以包括新功能，例如临床环境之外的患者随访。结论本研究代表了在国际，多中心环境中首次使用ePRO系统来收集多语言PRO。MoPat2已在欧洲皮肤病学研究中由临床医生和患者进行了评估，从而获得了很高的用户满意度。该系统将得到进一步开发，以包括新功能，例如临床环境之外的患者随访。