Like many other chronic diseases, every allergic patient has different characteristics based on clinical course, treatment responsiveness and disease outcomes, which are associated with the genetic and epigenetic control of molecular mechanisms and environment. This variability necessitates the establishment of patient-tailored and precision approaches in handling allergic disorders. Better understanding of the underlying pathophysiological mechanisms for the development of allergic disorders will provide more rationale strategies based on individual cases in controlling and treating these disorders. Endotyping, phenotyping, genotyping and theratyping, and biomarkers are keywords in this area and have been gaining lots of attention in the field of precision medicine, which aims to revolutionize patient care and develop better prevention and treatment strategies. In addition, precision health is a new concept that brings precise approaches to the scene for being healthy and prevention of allergic disease and asthma. The specialty of allergy has a leading role in the field, because allergen-specific immunotherapy started 105 years ago, and is historically a leading personalized/precision medicine approach in all medicine disciplines providing the possibility of cure in an individualized manner instead of conventional symptomatic treatments.

中文翻译：

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过敏性疾病和哮喘的精密/个性化医学。

像许多其他慢性疾病一样，每位过敏患者在临床过程，治疗反应性和疾病结局方面都有不同的特征，这些特征与分子机制和环境的遗传和表观遗传控制有关。这种可变性使得必须建立针对患者的精确方法来处理过敏性疾病。更好地了解过敏性疾病发展的潜在病理生理机制将基于控制和治疗这些疾病的个案提供更多的基本策略。内分型，表型，基因型和治疗，以及生物标志物是这一领域的关键词，在精密医学领域已引起广泛关注，旨在彻底改变患者护理并制定更好的预防和治疗策略。此外，精准健康是一个新概念，为健康和预防过敏性疾病和哮喘带来了精确的方法。过敏的专科在该领域起着主导作用，因为过敏原特异性的免疫疗法始于105年前，并且在所有医学学科中一直是领先的个性化/精密医学方法，提供了以个性化方式代替常规对症治疗的可能性。