Abstract

Four hitherto unknown aristolane-type sesquiterpenes, including one novel 8,9-secoaristolane, namely secoaristolenedioic acid (1), two aristolone derivatives, namely 1α,2β-dihydroxyaristolone (2), 9-epidebilon (3), and one rare aristolane-chalcone hybrid, namely 3′-hydroxynardoaristolone A (4) were isolated from the ethanol extract of the roots and rhizomes of Nardostachys chinensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. In addition, the structure of aristolanhydride, recently isolated from the same species, was corrected by reanalysis of the published NMR data.

Graphical Abstract

中文翻译：

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甘松中的马兜铃烷型倍半萜类化合物和马兜铃酸酐的修订结构。

 抽象的

四种迄今为止未知的马兜铃烷型倍半萜，包括一种新型8,9-开环阿里斯托烷，即开环阿里斯托烯二酸( 1 )，两种马兜铃酮衍生物，即1α , 2β-二羟基马兜铃酮( 2 )，9-epidebilon( 3 )，以及一种罕见的马兜铃酮从甘松根和根茎的乙醇提取物中分离得到马兜铃烷-查耳酮杂合体，即3'-羟基甘松马里斯托酮A( 4 )。在广泛的光谱分析的基础上阐明了它们的结构。此外，最近从同一物种中分离出的马兜铃酸酐的结构通过对已发表的核磁共振数据的重新分析进行了修正。

 图解摘要