The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the development of these pathologies. A better understanding of the underlying mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or prophylactic strategies. This review is aimed to present the current knowledge of adipose tissue inflammation associated with obesity.

中文翻译：

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肥胖和发炎。

肥胖症的患病率最近急剧增加，并导致各种病理状况的患病率增加，包括2型糖尿病，非酒精性脂肪肝疾病，哮喘，各种类型的癌症，心血管和神经退行性疾病等。越来越多的证据表明，脂肪组织中存在局部炎症，继而促使全身性低度炎症作为促成这些病理发展的主要力量。需要更好地了解肥胖引起的脂肪组织炎症背后的潜在机制，以开发有效的治疗或预防策略。这篇综述旨在介绍与肥胖有关的脂肪组织炎症的最新知识。