ABSTRACT The aim of this meta-analysis is to summarize the available evidence on the social and demographic determinants of health-related quality of life (QoL) for HIV-infected populations in order to provide a direction to policy makers, planners, and program developers on how best to use their resources to improve the QoL of HIV-infected people. PubMed, Science Direct, Web of Science, and Cochrane electronic databases were searched (up to February 2017) to identify the relevant studies. A meta-analysis was conducted with procreate polled odds ratios (ORs and β) and the confidence intervals of 95% on determining factors of QoL in social and demographic terms. Random effect model was applied to calculate pooled estimation, due to varied sampling methods of researches. In total, 5607 papers were identified from 4 databases and additional search in reference lists. Of these, 2107 articles were selected for full-text review. We included 19 studies that met the eligibility criteria. The pooled effect size shows a relative positive impact of social support for QoL among HIV/AIDS patients and its lower boundary is about 0.61 and the higher about 1.49. The pooled effect size has a considerable negative impact stigma on people who live with HIV/AIDS (PWLHs’) QoL ranges from −0.34 to −0.32. Low socioeconomic status (poverty situation) was found to have a degenerative impact with PWLHs’ QoL. Our finding indicates an association between younger 35 and QoL is negative with a relatively wide range, the minimum level of education has a weak association with PWLHs’ QoL (ES: 0.14–0.2). There are several sociodemographic determinants of QoL among PWLHs and in this study, we found that stigma, low level of socioeconomic status, and being younger than 35 years old have a negative association with QoL, while the social support showed a positive association and a minimum level of education did not show a rigorous negative or positive association.

中文翻译：

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艾滋病毒/艾滋病感染者生活质量的社会和人口统计学决定因素：荟萃分析的证据。

摘要这项荟萃分析的目的是总结有关艾滋病毒感染人群健康相关生活质量（QoL）的社会和人口统计学决定因素的现有证据，以便为政策制定者，规划人员和计划制定者提供指导关于如何最好地利用他们的资源来改善艾滋病感染者的生活质量。搜索PubMed，Science Direct，Web of Science和Cochrane电子数据库（截至2017年2月）以识别相关研究。进行荟萃分析，以极高的民意调查比值比（ORs和β）和95％的置信区间确定社会和人口统计学QoL的因素。由于研究的抽样方法多种多样，因此采用随机效应模型来计算合并估计。总共，从4个数据库中识别出5607篇论文，并在参考文献列表中进行了其他搜索。其中，选择2107篇文章进行全文审查。我们纳入了19项符合资格标准的研究。汇总效应量显示，HIV / AIDS患者对QoL的社会支持具有相对积极的作用，其下界约为0.61，较高约为1.49。合并效应量对感染艾滋病毒/艾滋病的人的负面影响（QOL）范围为-0.34至-0.32。低的社会经济地位（贫困状况）被发现对残疾人士的生活质量有负面影响。我们的发现表明，年龄在35岁以下的年轻人与QoL之间的关联为负，且范围较广，最低教育水平与PWLH的QoL关联较弱（ES：0.14-0.2）。