The 2011 World Health Organization global report on HIV and/or AIDS estimated that sub-Saharan Africa comprised 67% of the global HIV burden, with a current estimate of 5.9 million cases in South Africa. Since the introduction of antiretroviral therapy, there has been an increase in the incidence of non-AIDS-defining cancers. Gestational trophoblastic neoplasm (GTN) is a rare pregnancy-related disorder with an incidence ranging from 0.12-0.7/1000 pregnancies in Western nations. The overall cure rate is about 90%. Response to treatment for GTN is generally favourable; but the sequelae of HIV and/or AIDS, the resultant low CD4 counts, comorbidities, poor performance status and the extent of metastatic disease in patients receiving chemotherapy, compromise the prognosis and survival.

中文翻译：

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妊娠滋养细胞肿瘤和感染艾滋病毒和/或艾滋病的妇女。

2011年世界卫生组织关于艾滋病毒和/或艾滋病的全球报告估计，撒哈拉以南非洲占全球艾滋病毒负担的67％，目前估计南非有590万例。自从引入抗逆转录病毒疗法以来，非艾滋病定义癌症的发病率有所增加。妊娠滋养细胞肿瘤（GTN）是一种罕见的妊娠相关疾病，在西方国家的发病率范围为0.12-0.7 / 1000怀孕。总体治愈率约为90％。一般而言，对GTN治疗的反应良好；但是，HIV和/或AIDS的后遗症，导致化疗患者的CD4计数低，合并症，不良表现和转移性疾病的程度降低了预后和生存率。