Two young dogs were referred to the Veterinary Medical Teaching Hospital of Konkuk University, one for examination of vaginal discharge and the other after being hit by a car. Dog 1 exhibited a high neutrophil count on Gram-stained vaginal smears, marked leukocytosis on a complete blood count, and uterine enlargement on ultrasonography. In dog 2, a markedly enlarged right uterine horn containing echogenic debris was found incidentally on ultrasonography. A tentative diagnosis of pyometra was made in both cases and ovariohysterectomy was performed. Purulent material was collected from each uterine horn and submitted separately for aerobic and anaerobic bacterial culture; all culture results were negative. The white blood cell count revealed normal limits 2 days post operation in dog 1 and 4 days post operation in dog 2. Positive bacterial cultures are usually obtained from dogs with pyometra, and antibiotic selection is based on the results of culture and sensitivity testing in the event of failure of empiric antibiotic therapy. However, in the cases reported here, no bacterial growth was identified from the uterine samples despite the presence of purulent material. A short course of empiric antibiotic therapy was administered. This is the first known report describing sterile pyometra in dogs.

中文翻译：

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两只狗的无菌子宫蓄脓

两只幼犬被转诊至建国大学兽医教学医院，一只检查白带，另一只被车撞。狗 1 在革兰氏染色的阴道涂片上显示出高中性粒细胞计数，在全血计数上显示出明显的白细胞增多，在超声检查上显示出子宫增大。在狗 2 中，在超声检查中偶然发现了一个明显扩大的右子宫角，其中含有回声碎片。两个病例均初步诊断为子宫蓄脓，并进行了卵巢子宫切除术。从每个子宫角收集脓性物质，分别进行需氧和厌氧细菌培养；所有培养结果均为阴性。白细胞计数显示，狗 1 术后 2 天和狗 2 术后 4 天的白细胞计数正常。阳性细菌培养通常从患有子宫积脓的狗身上获得，抗生素的选择是基于培养结果和在经验性抗生素治疗失败的情况下的敏感性测试。然而，在此处报告的病例中，尽管存在化脓物质，但未从子宫样本中发现细菌生长。给予短期经验性抗生素治疗。这是第一份描述犬无菌子宫蓄脓的已知报告。给予短期经验性抗生素治疗。这是第一份描述犬无菌子宫蓄脓的已知报告。给予短期经验性抗生素治疗。这是第一份描述犬无菌子宫蓄脓的已知报告。