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Web-based indicated prevention of common mental disorders in university students in four European countries - Study protocol for a randomised controlled trial.
Internet Interventions ( IF 3.6 ) Pub Date : 2019-04-01 , DOI: 10.1016/j.invent.2018.02.004
Peter Musiat 1 , Rachel Potterton 1 , Gemma Gordon 1 , Lucy Spencer 1 , Michael Zeiler 2 , Karin Waldherr 3 , Stefanie Kuso 2, 3 , Martina Nitsch 3 , Tanja Adamcik 3 , Gudrun Wagner 2 , Andreas Karwautz 2 , David Daniel Ebert 4 , Alyson Dodd 5 , Barbara Dooley 6 , Amy Harrison 7 , Emma Whitt 8 , Mark Haselgrove 8 , Helen Sharpe 9 , Jo Smith 10 , Rosie Tressler 11 , Nicholas Troop 12 , Chantal Vinyard 10 , Dennis Görlich 13 , Jenny Beecham 14 , Eva Bonin 14 , Corinna Jacobi 15 , Ulrike Schmidt 1
Affiliation  

Background Mental disorders and their symptoms are highly prevalent in the university student population, and the transition from secondary to tertiary education is associated with a rise in mental health problems. Existing web-based interventions for the prevention of common mental disorders in student populations often focus on just one disorder and have not been designed specifically for students. There is thus a need for transdiagnostic, student-specific preventative interventions that can be widely disseminated. This two-arm, parallel group randomised controlled trial aims to evaluate the effectiveness and cost-effectiveness of a web-based transdiagnostic mental health problem prevention programme (PLUS) across several universities in four countries. Method Students (N = 5550) will be recruited through a variety of channels and asked to complete a personality assessment to determine whether they are at high risk for developing common mental disorders. Students at high risk will be randomly allocated to either PLUS or a control intervention, which provides practical support around issues commonly experienced at university. Students at low risk will be allocated to the control intervention. Both intervention groups will be assessed at baseline, 4 weeks, 3 months, 6 months and 12 months after randomisation. Depression and generalised anxiety, assessed using the Patient Health Questionnaire and the Generalised Anxiety Disorder scales, will form the primary outcomes in this study. Secondary outcome measures include alcohol and drug use, eating behaviour, self-esteem, and quality of life. The cost-effectiveness of the intervention will also be evaluated. Conclusions This study will contribute to understanding the role of transdiagnostic indicated web-based interventions for the prevention of common mental disorders in university students. It will also be one of the first studies to investigate the cost-effectiveness of such interventions. Trial Registration This trial was registered in the ISRCTN register (ISRCTN15570935) on 12th February 2016.

中文翻译:

基于网络的四个欧洲国家大学生常见精神障碍的预防 - 随机对照试验的研究方案。

背景精神障碍及其症状在大学生群体中非常普遍,从中学教育到高等教育的过渡与心理健康问题的增加有关。现有的用于预防学生群体中常见精神障碍的基于网络的干预措施通常只关注一种障碍,并不是专门为学生设计的。因此,需要可以广泛传播的跨诊断、针对学生的预防性干预措施。这项双臂、平行组随机对照试验旨在评估四个国家的几所大学的基于网络的跨诊断心理健康问题预防计划 (PLUS) 的有效性和成本效益。方法 学生 (N = 5550) 将通过多种渠道招募,并要求他们完成性格评估,以确定他们是否有患上常见精神障碍的高风险。高风险学生将被随机分配到 PLUS 或控制干预,这为大学常见的问题提供实际支持。低风险学生将被分配到控制干预。两个干预组将在基线、随机化后 4 周、3 个月、6 个月和 12 个月进行评估。使用患者健康问卷和广泛性焦虑症量表评估的抑郁症和广泛性焦虑症将构成本研究的主要结果。次要结果指标包括酒精和药物使用、饮食行为、自尊和生活质量。还将评估干预的成本效益。结论 本研究将有助于了解跨诊断指示的基于网络的干预措施在预防大学生常见精神障碍中的作用。这也将是调查此类干预措施成本效益的首批研究之一。试验注册 本试验于 2016 年 2 月 12 日在 ISRCTN 注册 (ISRCTN15570935) 中注册。
更新日期:2019-04-01
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