ABSTRACT Childhood arterial ischemic stroke often involves basal ganglia and thalamus but little is known about neuropsychological outcomes in this group. We examined intellectual ability, academics, attention, executive function, and psychological diagnoses in children and adolescents (6–20 years of age) with childhood stroke involving the basal ganglia (n = 32) or thalamus (n = 12). Intellectual ability was age-appropriate but working memory was significantly lower than expected. Compared to the normative mean, the stroke group exhibited significantly weaker performance in reading comprehension, math fluency, attention, and greater challenges with executive function. Children with basal ganglia stroke had weaker working memory and were more likely to receive diagnoses of Attention Deficit Hyperactivity Disorder and Anxiety Disorder than those with thalamic stroke. Lesion size was most important in predicting working memory ability, whereas age at stroke and age at test were important in predicting academic ability.

中文翻译：

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儿童皮层下中风后认知和学业结果的预测因素

摘要 儿童动脉缺血性卒中通常累及基底神经节和丘脑，但对该组的神经心理学结果知之甚少。我们检查了患有基底节（n = 32）或丘脑（n = 12）的儿童中风的儿童和青少年（6-20 岁）的智力、学业、注意力、执行功能和心理诊断。智力与年龄相称，但工作记忆明显低于预期。与正常平均值相比，中风组在阅读理解、数学流畅性、注意力和执行功能挑战方面表现出明显较弱的表现。与丘脑卒中儿童相比，基底神经节卒中儿童的工作记忆较弱，更容易被诊断为注意力缺陷多动障碍和焦虑症。病变大小对预测工作记忆能力最重要，而中风年龄和测试年龄对预测学习能力很重要。