Perfluorinated compounds (PFCs) are used in manufacturing food contact materials, including non-stick cookware coatings and oil- and moisture-resistant paper coatings. The chemical stability of PFCs poses an issue for human safety, as they do not degrade well naturally and hence may accumulate in the body. In terms of food safety, since dietary intake is thought to be a major source of exposure to PFCs, it is necessary to assess the migration of PFCs from food packaging articles to food under typical cooking and storage conditions. An analytical method was developed for assessing the migration of 16 PFCs from food contact materials to food simulants using liquid chromatography–tandem mass spectrometry. The applicability of the method for regular inspection was assessed by monitoring 312 samples. Based on the results of the exposure assessment, all food contact materials deemed to be safe for use, which evaluated migrated concentrations and dietary food intake.

全氟化合物（PFC）用于制造食品接触材料，包括不粘炊具涂料和耐油防潮纸涂料。PFC的化学稳定性会对人体安全造成影响，因为它们无法自然降解，因此可能在体内积聚。在食品安全方面，由于饮食摄入被认为是接触PFC的主要来源，因此有必要评估在典型的烹饪和储存条件下PFC从食品包装制品向食品的迁移。开发了一种分析方法，用于使用液相色谱-串联质谱法评估16种PFC从食品接触材料到食品模拟物的迁移。通过监测312个样品，评估了该方法对常规检查的适用性。根据暴露评估的结果，