当前位置: X-MOL 学术Curr. Med. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Metabolomic Biomarkers in Gynecology: A Treasure Path or a False Path?
Current Medicinal Chemistry ( IF 3.5 ) Pub Date : 2020-06-30 , DOI: 10.2174/0929867326666190104124245
Igor Govorov 1, 2 , Stanislav Sitkin 1, 2, 3 , Tatyana Pervunina 1, 2 , Alexey Moskvin 2 , Denis Baranenko 2 , Eduard Komlichenko 1, 2
Affiliation  

Omic-technologies (genomics, transcriptomics, proteomics and metabolomics) have become more important in current medical science. Among them, it is metabolomics that most accurately reflects the minor changes in body functioning, as it focuses on metabolome – the group of the metabolism products, both intermediate and end. Therefore, metabolomics is actively engaged in fundamental and clinical studies and search for potential biomarkers. The biomarker could be used in diagnostics, management and stratification of the patients, as well as in prognosing the outcomes. The good example is gynecology, since many gynecological diseases lack effective biomarkers. In the current review, we aimed to summarize the results of the studies, devoted to the search of potential metabolomic biomarkers for the most common gynecological diseases.



中文翻译:

妇科代谢组学生物标记物:宝藏路径还是错误路径?

眼科学技术(基因组学,转录组学,蛋白质组学和代谢组学)在当前医学中变得越来越重要。其中,代谢组学最准确地反映了人体功能的细微变化,因为它专注于代谢组–中间和最终代谢产物。因此,代谢组学积极参与基础和临床研究,并寻找潜在的生物标志物。该生物标志物可用于患者的诊断,管理和分层以及预后。妇科是一个很好的例子,因为许多妇科疾病缺乏有效的生物标志物。在当前的审查中,我们旨在总结研究结果,这些研究致力于寻找最常见的妇科疾病的潜在代谢组学生物标志物。

更新日期:2020-06-30
down
wechat
bug