The food and health applications of bioactive peptides have grown remarkably in the past few decades. Current elucidations have shown that bioactive peptides have unique structural arrangement of amino acids, conferring distinct functionalities, and molecular affinity characteristics. However, whereas interest in the biological potency of bioactive peptides has grown, cost-effective techniques for monitoring the structural changes in these peptides and how these changes affect the biological properties have not grown at the same rate. Due to the high binding affinity of aptamers for other biomolecules, they have a huge potential for use in tracking the structural, conformational, and compositional changes in bioactive peptides. This review provides an overview of bioactive peptides and their essential structure-activity relationship. The review further highlights on the types and methods of synthesis of aptamers before the discussion of the prospects, merits, and challenges in the use of aptamers for bioaffinity interactions with bioactive peptides.

中文翻译：

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适体：在生物活性肽应用中新兴的一类生物亲和配体。

在过去的几十年中，生物活性肽在食品和健康方面的应用显着增长。当前的研究表明，生物活性肽具有独特的氨基酸结构排列，赋予不同的功能性和分子亲和性。然而，尽管人们对生物活性肽的生物学效能的兴趣有所增长，但用于监视这些肽的结构变化以及这些变化如何影响生物学特性的具有成本效益的技术并未以相同的速度增长。由于适体对其他生物分子的高结合亲和力，它们在追踪生物活性肽的结构，构象和组成变化方面具有巨大的潜力。这篇综述概述了生物活性肽及其基本的结构-活性关系。