More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed fundamental insights into our understanding of axon guidance mechanisms, neural differentiation, and early cell fate decisions. What is less understood is how a group of neurons from disparate anterior-posterior axial positions, lineages and developmental periods of neurogenesis coalesce to form a functional circuit. Using neurogenetic techniques developed in Drosophila it is now possible to study the neural substrates of behavior at single cell resolution. New mapping tools described in this review, allow researchers to chart neural connectivity to better understand how an anatomically simple organism performs complex behaviors.

中文翻译：

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驱动果蝇幼虫运动的神经回路。


30多年来对果蝇神经发生的研究揭示了我们对轴突引导机制、神经分化和早期细胞命运决定的理解的基本见解。人们不太了解的是，来自不同前后轴位置、谱系和神经发生发育时期的一组神经元如何结合形成功能回路。利用在果蝇中开发的神经遗传学技术，现在可以在单细胞分辨率下研究行为的神经基础。本综述中描述的新绘图工具使研究人员能够绘制神经连接图，以更好地了解解剖学上简单的生物体如何执行复杂的行为。