Much of the fear and uncertainty around Zika epidemics stem from potential association between Zika virus (ZIKV) complications on infected pregnant women and risk of their babies being born with microcephaly and other neurological abnormalities. However, much remains unknown about its mode of transmission, diagnosis and long-term pathogenesis. Worries of these unknowns necessitate the need for effective and efficient psychosocial programs and medical-legal strategies to alleviate and mitigate ZIKV related burdens. In this light, local and global efforts in maintaining fundamental health principles of moral, medical and legal decision-making policies, and interventions to preserve and promote individual and collectiveHuman Rights, autonomy, protection of the most vulnerable, equity, dignity, integrity and beneficence that should not be confused and relegated by compassionate humanitarian assistance and support. This paper explores the potential medical and ethical-legal implications of ZIKV epidemics emergency response packages and strategies alongside optimizing reproductive and mental health policies, programs and best practice measures. Further long-term cross-borders operational research is required in elucidating Zika-related population-based epidemiology, ethical-medical and societal implications in guiding evidence-based local and global ZIKV maternal-child health complications related approaches and interventions. Core programs and interventions including future Zika safe and effective vaccines for global Zika immunization program in most vulnerable and affected countries and worldwide should be prioritized.

中文翻译：

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扩大预防和控制策略中寨卡病毒流行并发症的伦理、法律和社会考虑。


围绕寨卡流行病的大部分恐惧和不确定性源于受感染孕妇的寨卡病毒（ZIKV）并发症与其婴儿出生时患有小头畸形和其他神经异常的风险之间的潜在关联。然而，关于其传播方式、诊断和长期发病机制仍有很多未知之处。由于对这些未知因素的担忧，需要有效且高效的心理社会计划和医疗法律策略来减轻和减轻寨卡病毒相关的负担。有鉴于此，地方和全球努力维护道德、医疗和法律决策政策的基本健康原则，并采取干预措施，以维护和促进个人和集体的人权、自主权、保护最弱势群体、公平、尊严、正直和仁慈不应将这一点与富有同情心的人道主义援助和支持混淆或贬低。本文探讨了 ZIKV 流行病应急响应方案和策略的潜在医学和伦理法律影响，同时优化生殖和心理健康政策、计划和最佳实践措施。需要进一步开展长期跨境业务研究，阐明寨卡病毒相关的人群流行病学、伦理医学和社会影响，以指导基于证据的当地和全球寨卡病毒母婴健康并发症相关方法和干预措施。应优先考虑核心计划和干预措施，包括未来为最脆弱和受影响国家以及全世界的全球寨卡免疫计划提供安全有效的寨卡疫苗。