Antibodies have traditionally served as the affinity reagents of choice in point-of-care diagnostic biosensors. However, this class of proteins is not ideally suited for this use, being poorly characterized and prone to thermal denaturation. Here, we present an activity-based assessment of an alternative engineered binding protein in a cellulose-based assay.

中文翻译：

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对工程超嗜热蛋白作为纸基诊断测试中的捕获剂进行基于活性的评估。


传统上，抗体被用作即时诊断生物传感器中选择的亲和试剂。然而，这类蛋白质并不理想地适合这种用途，因为其特性较差且易于热变性。在这里，我们在基于纤维素的测定中对替代工程结合蛋白进行了基于活性的评估。