Arsenic trioxide (As₂O₃), known as pi-shuang and the most toxic compound in traditional Chinese medicine, has been used as an antitumor agent for thousands of years. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural phenol that has significant anti-bacterial, anti-fungaI and antiaging activities. Our study aimed to examine the combined anticancer effects of As₂O₃ and resveratrol against human neuroblastoma SK-N-SH cells, and elucidate the underlying intracellular signaling.

中文翻译：

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三氧化二砷（As2O3）加白藜芦醇的新型组合可诱导人神经母细胞瘤SK-N-SH细胞程序性死亡。

三氧化二砷（As ₂ O ₃）被称为pi-shuang，是中药中毒性最高的化合物，数千年来一直用作抗肿瘤药。白藜芦醇（3,5,4'-三羟基-反式-二苯乙烯）是一种天然苯酚，具有显着的抗菌，抗真菌和抗衰老活性。我们的研究旨在检查As ₂ O ₃和白藜芦醇对人神经母细胞瘤SK-N-SH细胞的联合抗癌作用，并阐明潜在的细胞内信号传导。