Globalization of the biomedical research enterprise is occurring at an accelerating pace. Increasingly, scientific collaborations and contracts cross national borders. Assurance that the caliber of animal research and animal welfare are consistent among countries and that such animal use is done in a humane and conscientious manner is of significant concern to the scientific community, the general public, and other stakeholders. Bridging these international collaborations is a clear scientific imperative for statistical validity of the data and reproducibility of results to ensure the animal use is both meaningful and impactful. One way to mitigate the potential confounding effects that the welfare of the animals may have on the research data is to harmonize animal care and use practices and procedures worldwide. By harmonizing the care and use of animals, using high standards that are internationally accepted, research animal welfare and high-quality science will be achieved.

中文翻译：

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动物福利标准和国际合作。

生物医学研究企业的全球化正在加速发展。科学合作和合同越来越多地跨越国界。确保动物研究和动物福利的水平在各国之间是一致的，并且以人道和认真的方式进行这种动物使用，这是科学界，公众和其他利益相关者的重大关切。桥接这些国际合作对于数据的统计有效性和结果的可重复性显然是科学的当务之急，以确保动物的使用既有意义又有影响力。减轻动物福利可能对研究数据造成的潜在混杂影响的一种方法是在全球范围内协调动物保健和使用实践与程序。