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Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?
Nano Convergence ( IF 13.4 ) Pub Date : 2018-12-12 , DOI: 10.1186/s40580-018-0170-1
Woo-Jin Jeong 1 , Jiyoon Bu 1 , Luke J Kubiatowicz 1 , Stephanie S Chen 1 , YoungSoo Kim 2 , Seungpyo Hong 1, 3
Affiliation  

Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for biomedical applications. Synergism between the two promising classes of materials allows enhanced control over their biological behaviors, overcoming intrinsic limitations of the individual materials. Over the past decades, a myriad of PNCs has been developed for various applications, such as drug delivery, inhibition of pathogenic biomolecular interactions, molecular imaging, and liquid biopsy. This paper provides a comprehensive overview of existing technologies that have been recently developed in the broad field of PNCs, offering a guideline especially for investigators who are new to this field.

中文翻译:

肽-纳米颗粒缀合物:下一代诊断和治疗平台?

肽-纳米粒子缀合物(PNC)最近已成为生物医学应用的多功能工具。两类有前途的材料之间的协同作用可以增强对其生物行为的控制,克服单个材料的内在局限性。在过去的几十年里,无数的 PNC 被开发用于各种应用,例如药物输送、抑制致病性生物分子相互作用、分子成像和液体活检。本文全面概述了 PNC 广泛领域中最近开发的现有技术,特别为该领域的新手研究人员提供了指导。
更新日期:2018-12-12
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