Bright light in the blue-green range, administered in the early morning hours (prior to waking) may be particularly effective in shifting circadian rhythms and may increase gonadotropin production. Accordingly, we tested the feasibility and utility of a mask that emits bright blue/green light (compared to a similar mask that emitted a dim red light) towards the end of sleep in a randomized, placebo-controlled pilot study. The study included a three-day baseline period, immediately followed by a 12-day intervention period. Subjects were 30 healthy young men with minimal-mild depression. The bright light masks were well-tolerated and demonstrated adequate safety and feasibility. Following the intervention, those who wore the bright light mask demonstrated altered sleep timing suggestive of an earlier sleep period, and excreted a slight increase in follicle-stimulating hormone (FSH). Overall, light masks may prove useful in future studies of bright light therapy.

中文翻译：

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刚醒来之前施用的短波长光：一项初步研究

在清晨（醒来之前）使用蓝绿色范围内的明亮光线可能对改变昼夜节律特别有效，并可能增加促性腺激素的产生。因此，我们在一项随机、安慰剂对照的试点研究中测试了在睡眠结束时发出明亮蓝/绿光的面罩（与发出暗淡红光的类似面罩相比）的可行性和实用性。该研究包括三天的基线期，紧接着是 12 天的干预期。受试者是 30 名患有轻度抑郁症的健康年轻男性。强光面罩具有良好的耐受性，并证明了足够的安全性和可行性。干预后，那些戴着强光面罩的人表现出改变的睡眠时间，表明睡眠时间较早，并排出轻微增加的促卵泡激素（FSH）。总的来说，光罩可能在未来的亮光疗法研究中被证明是有用的。